Myrna Loy, The Thin Man (1934)
As one-half of married detective couple Nick and Nora Charles, Loy set a standard for lightning-fast witty repertoire that has rarely been matched — though outspoken fans Quentin Tarantino and Gilmore Girls creator Amy Sherman-Palladino certainly gave it a try. Loy helped define booze-soaked elegance throughout the Thin Man film series, but she also managed the much trickier balance of making her character’s love for her partner seem as exciting as the white-knuckle cases they were trying to crack. Loy was never nominated for her work, but her famous fans and industry peers campaigned for her to get an honorary life-time achievement award in 1991.Ten Great Comedic Performances That Deserved Oscar Nominations - Movies - BlackBook